E-ISSN: 1019-5157 ISSN: 2651-5024
Review
AIM: To define a new approach for primary vertebral tumors by discussing them in the light of 2020 World Health Organization (WHO) classification of bone tumors. MATERIAL and METHODS: In this study, we have discussed primary vertebral tumors in light of the 2020 Updated WHO Classification of Soft...
Original Investigation
AIM: To identify subgroups of cases with ventriculomegaly who will benefit from the cerebrospinal fluid (CSF) diversion procedures, n patients with post-traumatic hydrocephalus (PTH), and to identify the risk factors for its development to minimize its occurrence. MATERIAL and METHODS: We analyzed...
AIM: To investigate the changes in type II neuregulin-1 (NRG-1) during the regeneration process following autologous sciatic nerve transplantation in rats. MATERIAL and METHODS: In total, 40 healthy male Sprague-Dawley (SD) rats of clean grade with body weights between 250 g and 300 g were random...
AIM: To evaluate the efficiency of two models for prognostication of patients with isolated traumatic brain injury. MATERIAL and METHODS: The models developed with the data of the patients who applied within ten years were subjected to internal validation with the data of the patients who applied w...
AIM: To explore the surgical approach, technique and clinical effect of treating basilar bifurcation aneurysms. MATERIAL and METHODS: The clinical data of basilar bifurcation aneurysms treated by neuro-microsurgery are retrospectively analyzed in from September 2013 to September 2018. The aneurysms...
AIM: To explore the extent to which LNC01296 inhibits the miRNA-29c expansion genes Birc2 and Bak1 from causing damage induced by brain expansion and reimplantation. MATERIAL and METHODS: A total of 120 adult male experimental rats were divided to verify the effects of miRNA-29c and LNC01296 on b...
AIM: To illustrate the role of CBX8 -a protein involved in protein metabolism and chromatin regulation/acetylation- in glioma cells, especially in DNA damage repair pathways. MATERIAL and METHODS: Detect CBX8 expression in glioma cells and clinical samples by qPCR and Western blot. Overexpression ...
AIM: To design a practical, low-cost, and freely mobile training model for biportal endoscopic spine surgery to improve the surgeons? abilities in basic endoscopic skills, including triangulation, two-dimensional visualization, and one-handed control of the instruments. MATERIAL and METHODS: The tr...
AIM: To evaluate the efficacy and safety of combined transforaminal anterior epidural steroid injection (TAESI) and dorsal root ganglion pulsed radiofrequency (DRG-PRF) therapy on the radicular neck pain. MATERIAL and METHODS: The results of 84 patients with cervical radicular pain who underwent c...
AIM: To describe, and to evaluate the clinical and radiological characteristics of pediatric cavernous malformations (CMs) and the surgical approaches and their outcomes in a single center. MATERIAL and METHODS: We retrospectively reviewed pediatric patients with CMs that were treated in our cente...
AIM: To investigate the possible reasons of failed conservative treatment of osteoporotic thoracolumbar vertebral compression fractures (VCFs). Sagittal balance impairment may weaken union by increasing the load on the fracture line. Most osteoporotic vertebral fractures occur in the thoracolumbar...
AIM: To explore the efficacy and possible mechanisms of Low-intensity focused ultrasound (LIFU) in alleviating spasticity caused by Spinal cord injury (SCI). MATERIAL and METHODS: We selected male Sprague?Dawley rats as subjects and performed transverse injuries on the T9 vertebra of their spinal...
AIM: To detect the silent pulmonary thromboembolism (SPTE) frequency in patients who underwent craniotomy for a brain tumor, and to examine the correlation based on the data obtained from patients. MATERIAL and METHODS: Overall, 100 patients with brain tumors were included in the study. The mean a...
AIM: To assess the role of topical administration of tranexamic acid (TXA) on intraoperative and postoperative blood loss of patients undergoing posterior cervical laminectomy and lateral mass screw ?xation (PCLF) compared to a control group. MATERIAL and METHODS: The data of 88 patients that unde...
AIM: To evaluate the preoperative, operative, and postoperative outcomes of young and adult patients who underwent surgery for temporal lobe epilepsy related to hippocampal sclerosis (TLE-HS). MATERIAL and METHODS: This retrospective study assessed prospectively registered data collected from 2010...
AIM: To uncover factors that can predict the development of C5 palsy before surgery by evaluating several different parameters. MATERIAL and METHODS: A total of 177 patients who underwent surgery between 2015 and 2020 were included in the study. In total, C5 palsy was observed in 22 (12.4%) of our...
AIM: To investigate the importance of thoracic kyphosis (TK) for treatment preference in patients with Lenke Type 5C adolescent idiopathic scoliosis by comparing radiological outcomes of the patients who underwent selective fusion (SF) or nonselective fusion (NSF). MATERIAL and METHODS: Twenty-ni...
AIM: To investigate the surgical value of MER recordings and improve surgical technique by demonstrating the consistency between preoperative radiological STN volume and intraoperative neurophysiological STN length. MATERIAL and METHODS: Sixty-one patients with PD were enrolled. The volumes of the...
AIM: To investigate the predictive role of thiol/ disulfide homeostasis and Ischemia-modified albumin (IMA) levels for NTDs. MATERIAL and METHODS: A total of 71 pregnant women (31 with NTD and 42 healthy controls) were enrolled in this study. This prospective case-control study included pregnant w...
AIM: To compare the posterior cranial fossa (PCF) dimensions together with the measurements related to basilar invagination and platybasia of craniovertebral junction anomalies (CVJA) in CVJA (+) and CVJA (-) Chiari malformation Type 1 (CM1) patient groups with each other and with healthy control ...
AIM: To investigate the effects of a lumbar exercise program after single-level lumbar microdiscectomy on the recurrence of lumbar disc diseases. MATERIAL and METHODS: Between 2018 and 2021, 223 patients (104 women, 119 men, median age: 49 years) who received their first corrective surgery for lu...
AIM: To investigate the effect of vertebral artery stenosis (VAS) on the basilar artery tortuosity. MATERIAL and METHODS: A total of 158 patients (101 males; 57 females) were divided into two main groups depending on existence of the in the vertebral artery (VA). Then, these groups were divided in...
AIM: To investigate the efficacy of locally applied batimastat after laminectomy in preventing postoperative epidural fibrosis. MATERIAL and METHODS: Thirty-two Wistar albino male rats weighing 200?250 g were used. The rats were assigned to four different groups (I-Control group, II-sham group, II...
Technical Note
AIM: To present the ability of standard intraoperative neuronavigation to reliably identify the stylomastoid foramen, thus providing a quick and effective recognition of the facial nerve at its exit from the skull base. MATERIAL and METHODS: We describe the technical nuances of this procedure by p...
Letter to Editor