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¹The Johns Hopkins Hospital, School of Medicine, The Russell H. Morgan Department of Radiology and Radiological Science, Division of Neuroradiology, Section of Pediatric Neuroradiology, Baltimore, USA
²Erciyes University, School of Medicine, Department of Anatomy, Kayseri, Turkey
³The Johns Hopkins University, School of Medicine, The Russell H. Morgan Department of Radiology and Radiological Science, Division of Pediatric Radiology, Section of Pediatric Neuroradiology, Baltimore, USA
⁴Erciyes University, School of Medicine, Department of Biophysics, Kayseri, Turkey
⁵Erciyes University, School of Medicine, Department of Biostatistics, Kayseri, Turkey DOI : 10.5137/1019-5149.JTN.11567-14.0 Macrocerebellum is a rare entity characterized by an enlarged cerebellum. We describe a case of a 48-month-old child with macrocerebellum. We performed serial volumetric analysis [total brain volume (TBV) and cerebellar volume] over a period of 4 years. We analyzed the white matter microstructure in the cerebellum using diffusion tensor imaging (DTI). In our patient, we found higher fractional anisotropy (FA) and lower mean diffusivity (MD) in the cerebellar white matter compared to age-matched controls. Our results may represent accelerated myelination secondary to the abnormal cerebellar development. Keywords : Macrocerebellum, Cerebellar volume, Total brain volume, Volume ratio, Diffusion tensor imaging