E-ISSN: 1019-5157
ISSN: 2651-5024
Review
Pages: 535-548
DOI: 10.5137/1019-5149.JTN.35598-21.2
Alzheimer's disease (AD) is the most common type of dementia that causes disabilities in memory formation and activities of daily
living. Unfortunately, pharmacologic treatments have minimal and short-lasting effects on AD. With the increasing aging population,
investigations into therapeutic stra...
Original Investigation
Pages: 549-554
DOI: 10.5137/1019-5149.JTN.31074-20.2
AIM: To study the effect of lesion of the ventral tegmental area (VTA) on food intake, water intake, alcohol consumption, and alcohol
preference in the post-lesion period.
MATERIAL and METHODS: A group of 38 young adult healthy male Wistar albino rats was included in this experiment. The groups
o...
Pages: 555-559
DOI: 10.5137/1019-5149.JTN.32860-20.2
AIM: To assess the real challenges faced by neurosurgery residents in developing countries with limited resources and massive
workload.
MATERIAL and METHODS: This is a cross-sectional study based on the questionnaire filled by the neurosurgery trainees in
Pakistan directed at their training, stre...
Pages: 560-570
DOI: 10.5137/1019-5149.JTN.31889-20.3
AIM: To analyze the most-cited articles on cranial and spinal epidural hematomas (EDHs).
MATERIAL and METHODS: A title-specific search was performed on the Scopus database using the term ?epidural hematoma? in
June 2020, with no publication date restrictions. The top 100 most-cited articles were c...
Pages: 571-577
DOI: 10.5137/1019-5149.JTN.32794-20.6
AIM: To investigate the co-occurrence of the arcuate foramen (AF) variation of atlas and intracranial vertebral artery (V4) hypoplasia
and, therefore, to understand the pathophysiology of Barré-Lièou syndrome (BLS). The AF localizes on the vertebral artery (VA)
sulcus posterior to the atlas and ha...
Pages: 578-586
DOI: 10.5137/1019-5149.JTN.32559-20.4
AIM: To review both the surgical-related, and hardware-related adverse effects of deep brain stimulation (DBS) in a single center
over the last five years.
MATERIAL and METHODS: All patients who underwent DBS electrode implantation at the Akdeniz University Hospital during the
last five years par...
Pages: 587-594
DOI: 10.5137/1019-5149.JTN.23766-18.3
AIM: To investigate the protective role of Hippophae rhamnoides L. (Sea buckthorn, SBT) in cold plus immobilization stress-induced
oxidative and nitrosative stress in rats.
MATERIAL and METHODS: Thirty-two Wistar albino rats were randomly divided into four groups: control (i.p. physiological salin...
Pages: 595-602
DOI: 10.5137/1019-5149.JTN.34490-21.3
AIM: To reevaluate the medulloblastoma cases according to histomorphological and molecular features, and to investigate the
relationship between the prognostic factors of the new WHO classification by applying Beta-catenin, YAP1, GAP1, p53, and INI1
antibodies immunohistochemically.
MATERIAL and ...
Pages: 603-611
DOI: 10.5137/1019-5149.JTN.30283-20.3
AIM: To describe a new, minimally invasive, and safe access to foramen rotundum via the endoscopic endonasal trans-sinusoidal
route for trigeminal nerve blockage.
MATERIAL and METHODS: We studied 5 fresh cadavers bilaterally, and 10 pterygopalatine fossae and maxillary nerves using the
endoscopic...
Pages: 612-617
DOI: 10.5137/1019-5149.JTN.34049-21.3
AIM: To introduce, and to evaluate the efficacy of the trans-superior articular process (trans-SAP) approach utilizing visual trephine
in percutaneous endoscopic transforaminal lumbar discectomy (PETLD) for migrated lumbar disc herniation.
MATERIAL and METHODS: This study included 98 patients, 50 ...
Pages: 618-624
DOI: 10.5137/1019-5149.JTN.35313-21.2
AIM: To evaluate the impact of carnosine on Purkinje neurons in rats exposed to a 900 Mhz electromagnetic field.
MATERIAL and METHODS: This study evaluated 24 rats divided into the following three different groups: a control group, a group
exposed to the electromagnetic field, and a group that was...
Pages: 625-634
DOI: 10.5137/1019-5149.JTN.34918-21.2
AIM: To report the clinical outcomes of microdiscectomy (MD) and endoscope assisted discectomy (EAD) techniques via the
posterior approach in patients with cervical disc herniations (CDHs).
MATERIAL and METHODS: The data were obtained from retrospective review of the patient?s charts and the lates...
Pages: 635-640
DOI: 10.5137/1019-5149.JTN.35526-21.3
AIM: To investigate the pullout strength of a pedicle screw reinserted through the same trajectory
MATERIAL and METHODS: Fifty freshly frozen lamb L4 vertebrae were divided into the following five groups: Group 1, inserted
with a 5-mm pedicle screw; Group 2, inserted with a 5-mm pedicle screw foll...
Pages: 641-648
DOI: 10.5137/1019-5149.JTN.34728-21.2
AIM: To explain the association between vertebral body hypoplasia and degenerative changes in the discovertebral complex and
facet joints, and to assess the incidence of hypoplasia of the vertebral body at the L5 level.
MATERIAL and METHODS: A retrospective analysis was made of 3,100 patients aged...
Pages: 649-656
DOI: 10.5137/1019-5149.JTN.35770-21.2
AIM: To propose a treatment algorithm, and to assess spinal instability in patients diagnosed with spinal lymphoma.
MATERIAL and METHODS: Demographics, symptoms, tumor level and location, and presence of spinal instability were reviewed
in 22 patients with spinal lymphomas. Each patient's neurolog...
Pages: 657-661
DOI: 10.5137/1019-5149.JTN.36527-21.2
AIM: To determine the clinical value of anocutaneous reflex (AR) in children with neurogenic bladder due to spina bifida (SB).
MATERIAL and METHODS: Patients who were diagnosed with SB were prospectively evaluated; moreover, AR and bulbocavernous
reflex were examined. Patients were divided into th...
Pages: 662-666
DOI: 10.5137/1019-5149.JTN.35807-21.1
AIM: To compare and analyze the effects of cranial suture reconstruction and frontal frame retraction for surgical treatment of
premature closure of the sagittal suture.
MATERIAL and METHODS: Infants with premature closure of the sagittal suture were included in this study. All infants underwent
...
Pages: 667-672
DOI: 10.5137/1019-5149.JTN.36863-21.1
AIM: To validate a new particulate embolization method using degradable starch microspheres (DSM) and intraarterial exogenous
amylase administration, which allow for regulated temporary cerebral arterial embolization without compromising tissue perfusion.
MATERIAL and METHODS: Twenty-four male New...
Pages: 673-679
DOI: 10.5137/1019-5149.JTN.35843-21.3
AIM: To compare the perioperative outcomes between single-day combined or separate-day staged surgeries for cervical spinal
stenosis.
MATERIAL and METHODS: A retrospective cohort analysis was conducted on consecutive patients admitted at a single institution
between July 2015 and April 2019, who ...
Pages: 680-687
DOI: 10.5137/1019-5149.JTN.38252-22.3
AIM: To evaluate the effects of favipiravir (FVP) on cell viability and cytotoxicity in human degenerated primary intervertebral disc
(IVD) tissue cell cultures. Furthermore, the protein expressions of hypoxia-inducible factor 1 alpha (HIF-1α), nuclear factor-kappa-b
(NF-κB), and inter...
Pages: 688-696
DOI: 10.5137/1019-5149.JTN.37703-22.2
AIM: To analyze and to compare the factors that influence the recurrence of chronic subdural hematoma (CSDH) among patients
treated with subdural non-suction-assisted passive drainage, subgaleal suction-assisted active drainage, and without drainage.
MATERIAL and METHODS: We retrospectively evalua...
Case Report
Pages: 697-701
DOI: 10.5137/1019-5149.JTN.36394-21.1
Posterior communicating artery (PComA) aneurysms are common cerebral aneurysms. In cases of PComA aneurysms accompanied
by anatomical variations of PComA, such as hypoplasia, hyperplasia, or infundibular dilatation, it is challenging to completely
determine the relationship between the parent arte...
Technical Note
Pages: 702-706
DOI: 10.5137/1019-5149.JTN.35741-21.1
AIM: To describe a simple technique of angular adjustment of cerebral angiographic views that makes them similar to the surgical
field under the operation microscope.
MATERIAL and METHODS: The technique of angular adjustment consists of three steps: 1. Upside-down 180-degree rotation of
the stand...
Letter to Editor
Pages: 707
DOI: 10.5137/1019-5149.JTN.38180-22.0
Thanks to Reviewers