Issue release date: 12.11.2024
2Ataturk University, Faculty of Medicine, Department of Neurosurgery, Erzurum, Turkey
3Ataturk University, Faculty of Medicine, Department of Psychiatry, Erzurum, Turkey
4Ataturk University, Faculty of Medicine, Department of Pharmacology, Erzurum, Turkey
519 Mayıs University, Faculty of Medicine, Department of Neurosurgery, Samsun, Turkey
6Ataturk University, Faculty of Medicine, Department of Pathology, Erzurum, Turkey
7Gulhane Military Medical Academy, Department of Neurosurgery, Ankara, Turkey DOI : 10.5137/1019-5149.JTN.3933-10.2 AIM: The aim of this study was to investigate the effects of impulse noise on the epithelial cells of the choroid plexus.
MATERIAL and METHODS: Forty Sprague Dawley rats were used and divided into the 2 groups as control and study groups. In the control group, the rats did not suffer noise injury. The rats were exposed to impulse noise at 20 minute durations at 10 times each day for one month in study group. Then, the rats were sacrificed and the choroid plexuses were examined histologically. The number of cells was counted and the cells were analyzed.
RESULTS: There were clear signs of nuclear condensation and cell body shrinkage, suggesting the presence of apoptosis. Severe desquamation of villus and the cell loss were observed in the study group. The numbers of the normal cells decreased, and the number of apoptotic cells increased significantly (p<0.05).
CONCLUSION: Impulse noise causes apoptotic death of epithelial cells in the choroid plexus, decrease the normal cells and increase the apoptotic cells.
Keywords : Impulse noise, Choroid plexus, Apoptosis