Turkish Neurosurgery 1991 , Vol 2 , Num 1
SECRETORY MENINGIOMA A CONVENTIONAL HISTOCHEMICAL STUDY OF SIX CASES
Aydın SAV, Figen SOYLEMEZOGLU, Fahir ÖZER, Necmettin PAMİR, Sevgi KULLU, Gülsün EKİCİOGLU
Department of Pathology Department of Neurosurgery. Marmara University, School of Medidne, İstanbul, TURKEY Six meningiomas with abundant hyaline inclusions (pseudopsammoma bodies) were studied in means of a panel of conventional histochemistry. In all six cases, the inclusions were PAS-positive, diastase resistant and stained picrophilic (yellow-bright orange) with van Gieson. Negative staining was obtained by von Kosa, Congo red and Gomori's reticulin. A remarkable pericytic proliferation around the vessel wall was found in five cases. It is concluded that secretory meningioma is a distinct type of meningioma. It shows characteristic lightmicroscopic, ultrastructural and immunohistochemical features of epithelial and secretory differentiation. Keywords : Meningioma. Secretory meningioma, Hyaline inclusion, Histochemistry