E-ISSN: 1019-5157
ISSN: 2651-5024
Vol. 34, Issue 2 (2024)
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Review
Pages: 175-183
DOI: 10.5137/1019-5149.JTN.42926-22.2
AIM: To compare 1 and 2 level posterior lumbar interbody fusion (PLIF) to transforaminal lumbar interbody fusion (TLIF) techniques
in an effort to elucidate trends in overall radiological and clinical outcome, rate of complications, operation time, length of hospital
stay, reoperation rate, pseudo...
Original Investigation
Pages: 184-195
DOI: 10.5137/1019-5149.JTN.21876-17.5
AIM: To identify ependymoma (EPN) driver genes and key pathways, and also to illuminate the connection between prognosis of
EPN patients and expression levels of driver genes.
MATERIAL and METHODS: The gene expression profiles of GSE50161, GSE66354, GSE74195, and GSE86574 were analyzed to
figure ...
Pages: 196-205
DOI: 10.5137/1019-5149.JTN.36175-21.5
AIM: To determine the regulation of long non-coding RNA (lncRNA) MALAT1 on neuronal apoptosis during spinal cord injury (SCI)
and to explore its possible mechanisms.
MATERIAL and METHODS: The motor ability of SCI rat models and apoptosis in spinal cord tissue were evaluated. Primary spinal
cord n...
Pages: 206-215
DOI: 10.5137/1019-5149.JTN.36367-21.2
AIM: To determine the function of miR-384-5p in ketamine-induced neurotoxicity.
MATERIAL and METHODS: Neonatal hippocampal neurons were isolated from rats and treated with varying doses of ketamine.
RT?qPCR was utilized to measure the miR-384-5p level in ketamine-treated neurons. Neuronal viabilit...
Pages: 216-223
DOI: 10.5137/1019-5149.JTN.41081-22.3
AIM: To identify the predictive factors associated with the survival of patients with a diagnosis of primary spinal cord lymphoma
(PSCL).
MATERIAL and METHODS: The Surveillance, Epidemiology, and End Results (SEER) database was used in this study, which
involved 254 patients with PSCL. Data on th...
Pages: 224-234
DOI: 10.5137/1019-5149.JTN.38366-22.2
AIM: To elucidate the pro-tumorigenic role of IncRNA FOXD3-AS1 in glioblastoma.
MATERIAL and METHODS: The expression of miR-3918, FOXD3-AS1, and CCND1 was measured in glioblastoma cells and tissues
using reverse transcriptase quantitative PCR (RT-qPCR). The effect of FOXD3-AS1 silencing on the pro...
Pages: 235-242
DOI: 10.5137/1019-5149.JTN.42396-22.2
AIM: To investigate the feasibility and safety of lumbar spinous process split laminotomy by quantitative anatomic analysis.
MATERIAL and METHODS: Nine fresh adult human cadaveric specimens (including 45 lumbar segments) were divided into 3 groups randomly. The simulated operations and anatomic mea...
Pages: 243-249
DOI: 10.5137/1019-5149.JTN.42769-22.2
AIM: To evaluate systemic immune inflammation index (SII), systemic inflammatory response index (SIRI), multi-inflammatory index (MII), and prognostic nutrition index (PNI), and to compare them with the previously reported inflammation-related hematologic index in lumbar discectomy (LD).
MATERIAL a...
Pages: 250-255
DOI: 10.5137/1019-5149.JTN.43052-22.2
AIM: To compare the clinical and radiological outcomes of unilateral percutaneous kyphoplasty (PKP) surgeries performed using 3D
printing technology in patients with osteoporotic compression fractures to conventional unilateral PKP surgeries.
MATERIAL and METHODS: Patients with acute painful singl...
Pages: 256-262
DOI: 10.5137/1019-5149.JTN.42746-22.2
AIM: To evaluate the outcomes of dynamic stabilization in the multilevel degenerative spondylotic spine, and to compare the two
dynamic systems (Dynesys® and Orthrus®) to reveal the increasing role of dynamic systems in the management of the degenerative
spine.
MATERIAL and METHODS: A total of 74...
Pages: 263-267
DOI: 10.5137/1019-5149.JTN.43318-23.2
AIM: To examine the effects of regulating increased blood glucose levels on plasma ET-1 levels after severe head trauma in rats.
MATERIAL and METHODS: Traumatic diffuse brain injury-induced rats were followed for 7 days and were randomly divided into two groups of 36 rats. Pre- and posttraumatic bl...
Pages: 268-273
DOI: 10.5137/1019-5149.JTN.43174-23.1
AIM: To gain a better understanding of ischemia risk related to in-stent stenosis (ISS) or in-stent thrombosis (IST) of the middle
cerebral artery (MCA) and lenticulostriate arteries after flow-diverting devices (FDD) deployment from the internal carotid artery (ICA)
to proximal middle cerebral ar...
Pages: 274-282
DOI: 10.5137/1019-5149.JTN.43124-23.2
AIM: To identify the cage retropulsion (CR)-associated risk factors following lumbar interbody fusion (LIF).
MATERIAL and METHODS: Clinical data of patients who underwent LIF between January 2014 and December 2018 at three
medical centers were retrospectively analyzed. Patients were divided into C...
Pages: 283-288
DOI: 10.5137/1019-5149.JTN.43279-22.1
AIM: To analyze the demographic and clinical data of preterm or low birth weight newborns with periventricular hemorrhage.
MATERIAL and METHODS: This retrospective study analyzed patients admitted to the neonatal intensive care unit of a Bahcesehir University School of Medicine-Affiliated Hospital ...
Pages: 289-298
DOI: 10.5137/1019-5149.JTN.42740-22.2
AIM: To evaluate and compare postoperative ischemic complications to determine the risk factors for ischemic complications following revascularization surgery for Moyamoya disease (MMD).
MATERIAL and METHODS: This single-center retrospective study included 266 procedures between 2016 and 2021. Thre...
Pages: 299-307
DOI: 10.5137/1019-5149.JTN.42453-22.2
AIM: To explore the post-translational regulation of TRPV1, which plays an important role in neuropathic low back pain (NLBP).
MATERIAL and METHODS: qPCR was used to examine the gene mRNA levels. Western blot was used to examine the protein level. NLBP rat model was established for confirming what ...
Pages: 308-313
DOI: 10.5137/1019-5149.JTN.42971-22.2
AIM: To retrospectively analyze and compare ultrasound-assisted localization in situ with the traditional, open incision method for
treating cubital tunnel syndrome (CuTS).
MATERIAL and METHODS: We retrospectively analyzed 51 patients treated between 2018 and 2022 and categorized them
according t...
Pages: 314-324
DOI: 10.5137/1019-5149.JTN.44200-23.2
AIM: To examine the effect of cerebellar damage on the process of fracture healing.
MATERIAL and METHODS: A total of forty-two male rats were selected at random and subsequently allocated into three distinct
groups. The experimentals were divided into two subgroups within each group, with the inte...
Pages: 325-330
DOI: 10.5137/1019-5149.JTN.44593-23.3
AIM: To identify the patterns and types of neuorosurgical injuries sustained by victims of the double earthquakes affected ten cities with a population of 15 million in southern and central Türkiye.
MATERIAL and METHODS: In this descriptive observational study, we retrospectively analyzed the medic...
Pages: 331-342
DOI: 10.5137/1019-5149.JTN.46067-23.1
AIM: To share the surgical outcomes of 31 patients who underwent endoscopic endonasal transsphenoidal surgery (EETS) at a single center.
MATERIAL and METHODS: This retrospective analysis of 31 craniopharyngioma cases (2013?2022) with a minimum 6-month follow-up included demographic data, preoperati...
Pages: 343-350
DOI: 10.5137/1019-5149.JTN.45526-23.4
AIM: To investigate the therapeutic and neuroprotective effects of transcranial direct current stimulation (tDCS) application on the traumatic brain injury (TBI)-induced glutamate and calcium excitotoxicity and loss of motor and cognitive functions.
MATERIAL and METHODS: Forty rats were equally div...
Case Report
Pages: 351-357
DOI: 10.5137/1019-5149.JTN.20662-17.1
The paramedian forehead flap (PMFF) has been well described for nasal reconstruction. However, it has never been reported for use in the repair of high flow anterior skull base cerebrospinal fluid (CSF) leaks.
The patient was a 55 year-old African American male cocaine abuser who initially presente...
Pages: 358-361
DOI: 10.5137/1019-5149.JTN.21084-17.1
The coexistence of intracranial aneurysms and a meningioma is not a clinically common phenomenon. Here we present the case
of a meningioma of the left anterior clinoid process concurrent with a right clinoid aneurysm and a ruptured aneurysm of the left
posterior communicating artery (PcomA). Immed...
Pages: 362-366
DOI: 10.5137/1019-5149.JTN.29642-20.2
This study aimed to describe a novel endovascular strategy to help control blood flow used successfully to treat an infant with highflow
pial arteriovenous fistula (AVF).
Here, a single-hole high-flow nongalenic pial AVF was diagnosed in a 2.5 year-old infant is presented. After coil packing failu...
Pages: 367-375
DOI: 10.5137/1019-5149.JTN.44533-23.2
Parsonage-Turner Syndrome, or neuralgic amyotrophy, is an acute-onset upper limb and shoulder girdle palsy that can occur in a post-viral, post-surgical or idiopathic setting. There have also been some reported cases of the syndrome occurring following vaccinations. The pathophysiology of neuralgic ...