E-ISSN: 1019-5157
ISSN: 2651-5024
Vol. 33, Issue 6 (2023)
Full Metin PDF
Original Investigation
Pages: 921-928
DOI: 10.5137/1019-5149.JTN.31625-20.2
AIM: To understand the arachnoid microstructure during infrafloccular approach for facial nerve microvascular decompression
(MVD).
MATERIAL and METHODS: This study recruited 55 patients with hemifacial spasm who underwent MVD. Retrospective analyses of
the MVD surgical videos were performed to re...
Pages: 929-935
DOI: 10.5137/1019-5149.JTN.32824-20.5
AIM: To investigate the safety and efficacy of endoport-assisted endoscopic techniques for removing intraventricular lesions.
MATERIAL and METHODS: Data of patients with intraventricular lesions who were surgically treated by endoport-assisted
endoscopic resection between January 2018 and February...
Pages: 936-944
DOI: 10.5137/1019-5149.JTN.33034-20.2
AIM: To construct a reliable prediction model for pediatric atypical teratoid/rhabdoid tumor (ATRT) patients.
MATERIAL and METHODS: Population-based data of patients diagnosed with intracranial ATRT were extracted from the National
Cancer Institute?s Surveillance, Epidemiology, and End Results dat...
Pages: 945-950
DOI: 10.5137/1019-5149.JTN.37008-21.2
AIM: To explore the effect of pathogenesis-based individualised thrombectomy on the clinical results and prognoses of acute
intracranial large-artery occlusion.
MATERIAL and METHODS: A total of 151 patients were included in this prospective study and divided into the control group
(stent thrombec...
Pages: 951-959
DOI: 10.5137/1019-5149.JTN.36652-21.2
AIM: To examine the role and mechanism of colorectal tumor differential expression (CRNDE) in brain injury induced by ischemicreperfusion.
MATERIAL and METHODS: Sh-SY5Y cells were cultured, and oxygen and glucose deprivation/reperfusion (OGD/R) injury tests
were performed. The effects on SH-SY5Y c...
Pages: 960-966
DOI: 10.5137/1019-5149.JTN.40204-22.2
AIM: To conduct a meta-analysis for investigating the safety and efficacy of endoscopic third ventriculostomy (ETV) and extracranial
shunting for patients with obstructive hydrocephalus.
MATERIAL and METHODS: Randomized controlled trials (RCTs) of ETV and ventriculoperitoneal shunting (VPS) for ob...
Pages: 967-975
DOI: 10.5137/1019-5149.JTN.40189-22.2
AIM: To analyze the clinical and angiographic outcomes of interventional embolization under transarterial balloon protection
technique in patients with cavernous sinus dural arteriovenous fistulas.
MATERIAL and METHODS: In a single-center cohort of 30 patients undergoing cavernous sinus dural arte...
Pages: 976-981
DOI: 10.5137/1019-5149.JTN.37599-22.2
AIM: To investigate the neuroprotective effect of shilajit extract in experimental head trauma.
MATERIAL and METHODS: Three groups of 33 Sprague Dawley Albino strain male rats were included in the study. Group 1 (n=11):
trauma but not treated. Group 2 (n=11): trauma and treated with 0.5 mL / rat s...
Pages: 982-989
DOI: 10.5137/1019-5149.JTN.38289-22.1
AIM: To evaluate the effects of c-Jun N-terminal kinase (JNK) inhibition and signal blocking on hypoxia (hypoxia-inducible factor
1-alpha (HIF-1α)), differentiation and neurogenesis (bone morphogenetic protein (BMP4)), and the cytoskeleton (F-actin) in
glioblastoma multiforme cells (GBMCs).
...
Pages: 990-995
DOI: 10.5137/1019-5149.JTN.40343-22.5
AIM: To determine risk factors predicting chronic subdural hematoma (CSH) recurrence is a common type of intracranial hemorrhage
in elderly patients. Despite improved medical diagnosis and treatment, the reoperation rate remains high.
MATERIAL and METHODS: A retrospective review of 291 CSH patient...
Pages: 996-1004
DOI: 10.5137/1019-5149.JTN.41249-22.2
AIM: To compare, and to analyze the clinical and radiological signs between bidirectional and unidirectional screw fixation in single
level cervical discectomy and fusion surgery.
MATERIAL and METHODS: We retrospectively reviewed the data collected from 90 patients and divided them into the upper
...
Pages: 1005-1011
DOI: 10.5137/1019-5149.JTN.42017-22.2
AIM: To define the substantial role of the TLR4 signaling pathway in the MyD88-dependent pathway, and to evaluate the results of
TLR4 activation in nucleus pulposus cells. Moreover, we aim to associate this pathway with intervertebral disc degeneration and
magnetic resonance imaging (MRI) findings...
Pages: 1012-1016
DOI: 10.5137/1019-5149.JTN.42897-22.2
AIM: To investigate the effect of zinc oxide nanoparticles (ZnO-NPs) on neural tube development in early chicken embryos.
MATERIAL and METHODS: Fifty pathogen-free fertilized eggs were initially incubated for thirty hours. The eggs were divided into
5 groups. In the control group (C) the egg?s ape...
Pages: 1017-1027
DOI: 10.5137/1019-5149.JTN.42362-22.6
AIM: To investigate the effects of cerebrolysin on inflammation, oxidative stress, apoptosis, and neurologic recovery in the setting
of an experimental rabbit model of spinal cord ischemia/reperfusion injury (SCIRI).
MATERIAL and METHODS: Rabbits were randomly divided into five groups: control, is...
Pages: 1028-1037
DOI: 10.5137/1019-5149.JTN.42563-22.3
AIM: To study the effects of niacin, a water-soluble vitamin, on inflammation, oxidative stress and apoptotic processes observed
after mild traumatic brain injury (TBI).
MATERIAL and METHODS: A total of 25 Wistar albino male rats were randomly divided into control (n=9), TBI + Placebo group
(n=9)...
Pages: 1038-1046
DOI: 10.5137/1019-5149.JTN.42463-22.2
AIM: To compare the volumetric changes of intracranial arachnoid cysts (IACs) in different surgical techniques.
MATERIAL and METHODS: Sixty-six patients who underwent IAC surgery in our department between 2010 and 2020 were studied
retrospectively. Based on the surgical technique, clinical and vol...
Pages: 1047-1052
DOI: 10.5137/1019-5149.JTN.43115-22.1
AIM: To investigate the impact of obesity on postoperative morbidity and mortality in patients who underwent anterior cervical
discectomy and fusion (ACDF).
MATERIAL and METHODS: The American College of Surgeons? National Surgical Quality Improvement Project (NSQIP) files from
2006 to 2019 were q...
Pages: 1053-1057
DOI: 10.5137/1019-5149.JTN.42872-22.3
AIM: To review the cases of craniosynostosis secondary to ventricular shunting procedure.
MATERIAL and METHODS: We retrospectively evaluated the medical records of all pediatric patients with hydrocephalus who were
treated with ventriculoperitoneal shunt procedure between the years 2017 and 2021 a...
Pages: 1058-1068
DOI: 10.5137/1019-5149.JTN.43360-23.2
AIM: To evaluate the effect of intensive care follow-up and treatment methods on the prognosis of 28 patients admitted to the
pediatric intensive care unit (PICU) due to stroke.
MATERIAL and METHODS: The data of patients aged between 28 days and 18 years followed up between 2011 and 2021 were
rec...
Pages: 1069-1077
DOI: 10.5137/1019-5149.JTN.43003-22.3
AIM: To compare the postprocedural cerebral diffusion-weighted imaging (DWI) findings in cases of carotid stenosis (CS)-related
carotid plaques in terms of plaque morphology, degree of stenosis, and the use of a distal protection filter. Moreover, we used DWI
to assess the asymptomatic cerebral em...
Pages: 1078-1085
DOI: 10.5137/1019-5149.JTN.44032-23.2
AIM: To examine the outcomes of microsurgery only versus combined microsurgery and embolization in treating cerebral
arteriovenous malformations (AVM).
MATERIAL and METHODS: A total of 62 patients (34 male and 28 female) with Spetzler?Martin grade 3 (n=44) and grade 4 (n=18)
AVMs were examined. T...
Pages: 1086-1092
DOI: 10.5137/1019-5149.JTN.41102-22.6
AIM: To determine IDH1 R132H codon and the mRNA levels of PDK1, SLC2A1, EGFR, PTEN, and CD276 genes in brain tumors.
MATERIAL and METHODS: This study included 15 brain tumor tissues [pituitary adenoma (1), pilocytic astrocytoma (1), mixed
meningioma (2), mesothelial meningioma (2), atypical mening...
Pages: 1093-1098
DOI: 10.5137/1019-5149.JTN.44280-23.1
AIM: To investigate the possible association between COVID-19 infection and intraparenchymal hemorrhage (IPH) by examining
changes in the preoperative and postoperative periods, mortality, and the impact of COVID-19 on IPH survival times.
MATERIAL and METHODS: This cross-sectional retrospective an...
Pages: 1099-1105
DOI: 10.5137/1019-5149.JTN.44074-23.3
AIM: To investigate the relationship between epidural contrast spread patterns, and the treatment success of cervical interlaminar
epidural steroid injection (CIESI) for cervical radicular pain.
MATERIAL and METHODS: A total of 76 patients aged between 20 and 60 years who had neck and unilateral u...
Pages: 1106-1112
DOI: 10.5137/1019-5149.JTN.43674-23.1
AIM: To evaluate the effect of osteoplastic pterional craniotomy on temporal hollowing and its sequelae.
MATERIAL and METHODS: A total of 97 patients who underwent pterional craniotomy for an aneurysm were analyzed retrospectively.
Of these 97 patients, 63 underwent surgery via the conventional pt...
Pages: 1113-1119
DOI: 10.5137/1019-5149.JTN.43431-23.4
AIM: To assess the combined antitumor potential of theranekron (Trn) and cisplatin in neuroblastoma (NB), a pediatric tumor
characterized by high prevalence and mortality rates. The investigation involved examining the interaction between theranekron
(10-100 ?M) and cisplatin (40 ?M) within this c...
Pages: 1120-1125
DOI: 10.5137/1019-5149.JTN.44205-23.1
AIM: To determine if previous histological grading systems were sufficient or unreliable with a limited repository of modern techniques.
MATERIAL and METHODS: The pathology reports of pediatric neurosurgery patients between 2019-2022 were accessed. Data
on patients that needed unattainable further...
Pages: 1126-1131
DOI: 10.5137/1019-5149.JTN.45354-23.4
AIM: To compare the overall survival (OS), progression-free survival (PFS), and the impact of prognostic markers in unifocal and
multifocal IDH wild-type glioblastomas (GBMs).
MATERIAL and METHODS: This retrospective single-institutional study involved 177 GBM patients diagnosed between 2015 and
...
Case Report
Pages: 1132
DOI: 10.5137/1019-5149.JTN.42599-22.3
Oblique lateral interbody fusion (OLIF) has recently gained widespread use as a minimally invasive surgical procedure for degenerative
lumbar disease. OLIF has several advantages but can also lead to several possible complications. For example, although less
common, access through the retroperiton...