E-ISSN: 1019-5157
ISSN: 2651-5024
Vol. 36, Issue 5 (2026)
Full Metin PDF
Turkish Neuro -Excursion
Pages: 629-631
DOI: 10.5137/1019-5149.JTN.52460-26.0
Original Investigation
Pediatrics
A Population-Based Study of Pediatric and Adult Brainstem Glioma: Prognostic Nomograms for Overall and Cancer-Specific Survival
Pages: 632-645
DOI: 10.5137/1019-5149.JTN.49881-25.4
AIM: To establish an effective predictive model to inform clinical practice for brainstem glioma, a rare and highly aggressive tumor of the central nervous system, given the lack of prior retrospective studies using the SEER database that have included both pediatric and adult patients. MATERIAL and...
Neuro-Oncology
Functional Mapping-Guided Resection of Eloquent Diffuse Low-Grade Gliomas: A Single-Institution Experience from a Low-Middle Income Country
Pages: 646-657
DOI: 10.5137/1019-5149.JTN.49066-25.2
AIM: To report our experience in implementing functional mapping-guided resection for eloquent diffuse low-grade gliomas (DLGGs) in a low- and middle-income country (LMIC) setting. There are logistical barriers to achieving onco-functional balance through glioma surgery in LMICs. MATERIAL and METHOD...
Neuro-Oncology
Effect of Electrical Capacitance-Based Therapy on the Viability of U87 and T98-G Glioblastoma Cell Lines
Pages: 658-663
DOI: 10.5137/1019-5149.JTN.49048-25.3
AIM: To examine the selective cytotoxic effects of Electro-Capacitive Cancer Therapy (ECCT) on human glioblastoma (GBM) cell lines (U87-MG and T98-G) and to evaluate its impact on normal epithelial cells. MATERIAL and METHODS: U87-MG and T98-G glioblastoma cells, along with Beas-2B normal epithelial...
Cerebrovascular-Endovascular
Association of Pre-Existing Comorbidities with Inpatient Outcomes in Very Elderly Patients Presenting with Primary Intracerebral Hemorrhage
Pages: 664-670
DOI: 10.5137/1019-5149.JTN.48712-25.1
AIM: To explore presenting status and pre-existing comorbidities in very elderly patients and compare the inpatient management outcomes with younger counterparts in intracerebral hemorrhage (ICH). MATERIAL and METHODS: This ICH database is a retrospective cohort of 814 patients who presented with pr...
Cerebrovascular-Endovascular
Time-Dependent Neurovascular Effects of Thymoquinone on Basilar Artery Morphometry in a Rat Model of Subarachnoid Haemorrhage
Pages: 671-681
DOI: 10.5137/1019-5149.JTN.51344-26.2
AIM: To investigate the effects of short- and long-term intraperitoneal thymoquinone administration on basilar artery morphometry and cerebral perfusion in a subarachnoid haemorrhage (SAH) model. MATERIAL and METHODS: Forty-two adult male Wistar rats were randomly allocated to seven experimental gro...
Spine and Peripheral Nerves
Assessing the Association of Modic Changes and Clinical Outcome Before and After One-Level Lumbar Fusion
Pages: 682-688
DOI: 10.5137/1019-5149.JTN.49485-25.1
AIM: To assess the association between Modic changes (MCs) and clinical outcomes in patients undergoing one-level lumbar fusion surgery. MATERIAL and METHODS: A retrospective cohort study included patients (>18 years) with single-level DDD treated with one-level lumbar fusion from 2016 to 2020 at a ...
Spine and Peripheral Nerves
Practice Patterns of Percutaneous Vertebroplasty: A Survey of Neurosurgeons
Pages: 689-700
DOI: 10.5137/1019-5149.JTN.51506-26.2
AIM: To characterize current vertebral augmentation practices among neurosurgeons in Türkiye, with particular emphasis on patient selection, procedural approaches, complication experience, and postprocedure osteoporosis management. MATERIAL and METHODS: A national, cross-sectional, anonymous, web-ba...
Spine and Peripheral Nerves
Unilateral Biportal Endoscopy for Lumbar Disc Herniation and Spinal Stenosis: Clinical Outcomes and Complication Analysis
Pages: 701-709
DOI: 10.5137/1019-5149.JTN.50151-25.4
AIM: To evaluate clinical outcomes, complications, and pathological distribution in patients with lumbar disc herniation (LDH) and/or lumbar spinal stenosis (LSS) undergoing unilateral biportal endoscopic (UBE) surgery. MATERIAL and METHODS: This retrospective study included 127 patients with LDH an...
Spine and Peripheral Nerves
Effects of Felbamate on Tissue Caspase-3 Levels, Histopathology, and Neurological Function in Rats with Early Spinal Cord Ischemia-Reperfusion Injury
Pages: 710-717
DOI: 10.5137/1019-5149.JTN.51831-26.2
AIM: To evaluate the potential neuroprotective effect of felbamate in a rat model of spinal cord ischemia-reperfusion injury. MATERIAL and METHODS: Twenty-one male Wistar albino rats were randomly assigned to three groups (n=7 each): control, ischemia, and felbamate-treated. Transient spinal cord is...
Neuroanatomy
Anatomical Landmarks and Boundaries of the Endoscopic Sublabial Transmaxillary Approach to the Middle Cranial Fossa: A Cadaveric Study
Pages: 722-733
DOI: 10.5137/1019-5149.JTN.49296-26.4
AIM: To demonstrate the anatomical framework of the endoscopic sublabial transmaxillary approach (ESTA) to the middle cranial fossa (MCF). MATERIAL and METHODS: Six formalin-fixed human cadaveric heads injected with red and blue silicone were used for endoscopic dissections to define the surgical la...
Stereotactic and Functional
Evaluation of Group 1 Metabotropic Glutamate Receptors Expression After Lacosamide Treatment in a Kainic Acid–Induced Temporal Lobe Epilepsy Model
Pages: 734-743
DOI: 10.5137/1019-5149.JTN.50380-26.3
AIM: To investigate the effects of lacosamide (LCM), an antiepileptic agent, on group 1 metabotropic glutamate receptors (mGluR1 and mGluR5) expression in a temporal lobe epilepsy (TLE) model. MATERIAL and METHODS: Thirty-two rats were divided into 4 groups: (1) only burr hole without intrahippocamp...
General Neurosurgery and Miscellaneous-Others
Relationship Between Benign Intracranial Tumor Location and the Side of Spontaneous Cerebrospinal Fluid Leak
Pages: 744-754
DOI: 10.5137/1019-5149.JTN.49011-25.3
AIM: To present cases of spontaneous cerebrospinal fluid (CSF) rhinorrhea and otorrhea, and to conduct a systematic literature review examining the relationship between benign tumor location and the leak side. MATERIAL and METHODS: A PRISMA-based systematic review was conducted to evaluate studies o...
General Neurosurgery and Miscellaneous-Others
Evaluation of Perioperative Experiences of Patients Undergoing Awake Craniotomy: A Retrospective, Observational Study
Pages: 755-760
DOI: 10.5137/1019-5149.JTN.49789-26.1
AIM: To evaluate the satisfaction and experiences of patients who underwent awake craniotomy, a relatively uncommon procedure. MATERIAL and METHODS: Following institutional ethics committee approval, data from 60 patients who underwent awake craniotomy between January 2019 and September 2023 were re...
General Neurosurgery and Miscellaneous-Others
Surgical Management of Third Ventricular Colloid Cysts: The Fate of Open Microsurgery
Pages: 761-765
DOI: 10.5137/1019-5149.JTN.48794-25.2
AIM: To report our experience with the outcomes of open microsurgical management of third ventricular colloid cysts. MATERIAL and METHODS: This retrospective study presents the surgical outcomes of 33 patients who underwent open microsurgical resection—either through the interhemispheric transcallos...
Technical Note
Pages: 718-721
DOI: 10.5137/1019-5149.JTN.49758-25.2
Localising the lower cervical spine intraoperatively using conventional fluoroscopy with lateral projections has limitations. The main factor limiting the adequate visualisation of the cervicothoracic spaces is the superposition of the shoulder’s structures (soft tissue, muscle, and bone), which cre...
Case Report
Pages: 766-770
DOI: 10.5137/1019-5149.JTN.49701-25.2
Neuroenteric cysts (NCs) are rare benign lesions believed to originate from ectopic endodermal tissue. They are lined by gastrointestinal or respiratory epithelium capable of secreting mucin. Although most frequently located within the spinal canal, intracranial NCs are exceedingly rare and typicall...
Pages: 771-774
DOI: 10.5137/1019-5149.JTN.49761-25.3
This case report presents the first simultaneous occurrence of Chiari malformation type 1 and celiac disease in a 27-year-old male patient. To the best of our knowledge, there are no previously published cases in the literature. This rare association suggests that nutrient malabsorption caused by ce...
Pages: 775-779
DOI: 10.5137/1019-5149.JTN.49979-25.2
Intracranial solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms, and cases of tumor bleeding are rarely seen. While radiographically similar to meningioma, SFTs exhibit a more aggressive clinical course. The mainstay of treatment is surgical resection followed by adjuvant radiotherapy. We...