Spinal cord compression due to follicular thyroid carcinoma is rare. We report an unusual case of isolated vertebrae metastasis of follicular thyroid carcinoma presenting with spinal cord compression. It is unusual for this neoplasm to initially present as a single metastasis to the spine. Comprehensive preoperative work up for metastatic tumors of vertebrae is important. This should include evaluation of the thyroid gland consisting of detailed clinical history and physical examination.