Turkish Neurosurgery 2012 , Vol 22 , Num 1
Angiosarcoma of Skull in a Pregnant Woman: Case Report and Review of the Literature
Mohammad SAMADIAN1, Mohammad RAKHSHAN2, Karim HADDADIAN1, Omidvar REZAEI1, Seyed Ali Modaress ZAMANI1, Fatemeh KHORMAEE1
1Loghman-e-Hakim Medical Center, Shahid Beheshti University of Medical Sciences, Department of Neurosurgery, Tehran, Islamic Republic of Iran
2Loghman-e-Hakim Medical Center, Shahid Beheshti University of Medical Sciences, Department of Pathology, Tehran, Islamic Republic of Iran
DOI : 10.5137/1019-5149.JTN.3148-10.1 Angiosarcoma is a rare tumor of bone that uncommonly involves the skull. Primary neoplasms of the skull represent 2.6% of primary neoplasms of bone. We wish to report a case of angiosarcoma of he skull in an 18-year-old pregnant woman who presented with a rapidly growing left frontotemporal mass. Neuroimaging revealed a left frontotemporal mass with destruction of diploic space and both tables and with extension to the subgaleal and epidural spaces. The patient underwent surgery and the tumor was removed totally. Histological features of angiosarcoma were seen in the pathology study. She received adjuvant chemotherapy and radiation therapy. She has remained well during 6 years of follow-up with no evidence of recurrence. Angiosarcoma is a rare malignant bone tumor of vascular origin. Our case is the only female patient with skull angiosarcoma that has been reported so far. Keywords : Angiosarcoma, Skull, Neoplasm, Tumor
Corresponding author : Mohammad Samadřan, with:mdsamadian@hotmail.com