Turkish Neurosurgery 2017 , Vol 27 , Num 2
Imaging Findings of an Epidermoid Cyst with Malignant Transformation to Squamous Cell Carcinoma
Can OZUTEMIZ1,Emel ADA1,Ayca ERSEN2,Ercan OZER3,
1Dokuz Eylul University, School of Medicine, Department of Radiology, Izmir, Turkey
2Dokuz Eylul University, School of Medicine, Department of Pathology, Izmir, Turkey
3Dokuz Eylul University, School of Medicine, Department of Neurosurgery, Izmir, Turkey
DOI : 10.5137/1019-5149.JTN.12722-14.0 We report imaging findings of a 64-year-old male patient with a ruptured epidermoid cyst (EC) known to be constant over the 23-year follow-up and showing malignant transformation to squamous cell carcinoma (SCC). Computed tomography (CT) and magnetic resonance imaging (MRI) findings including diffusion weighted imaging (DWI), 1H+MR spectroscopy (MRS), dynamic susceptibility contrast perfusion (DSC) MRI of EC, and its rare complications are presented together with a review of the literature. Fluid-lowattenuated- inversion-recovery (FLAIR) and T1-weighted images with gadolinium are the best sequences together with DWI to show the relationship of the EC, the SCC and the border between. Primary brain SCC enhances mostly ring-like or peripherally, but diffuse enhancement is also possible. To our knowledge, no MRS and DSC findings have been reported in the literature yet. Keywords : Epidermoid cyst, Malignant transformation, Intracranial squamous cell carcinoma, Magnetic resonance imaging