Turkish Neurosurgery 2015 , Vol 25 , Num 5
Clinical Features and Surgical Treatment of Aggressive Meningiomas
Hongwei WANG, Shujiang NIU, Chuanwei WANG, Yuguang LIU
Qilu Hospital of Shandong University, Brain Science Research Institute of Shandong University, Department of Neurosurgery, Jinan, PR China DOI : 10.5137/1019-5149.JTN.10714-14.1 AIM: To explore the clinical features and surgical treatment of aggressive meningiomas (AMs).

MATERIAL and METHODS: Samples from 55 patients with AMs were analyzed, and their clinical characteristics, molecular biological mechanism, and surgical treatment were studied in combination with the literature.

RESULTS: The main clinical and imaging features of AMs included manifestations of local structures invaded by tumors, frequently irregular or flat tumors in shape, more obvious cerebral edema surrounding the tumors, seldom calcification of tumor, more frequent and typical dural tail sign, often absent white or black ring sign, partial or complete occlusion of venous sinus and hyperplasia and destruction of local skull. Simpson I resection was achieved in 31 cases, II in 13, III-IV in 11. No severe complications and death occurred after operation.

CONCLUSION: AMs have prominent clinical features. Appropriate surgery can provide a good therapeutic effect. Keywords : Aggressive meningiomas, Clinical manifestation, Imaging features, Surgical treatment

Corresponding author : Yuguang Lřu, NS3000@126.com