Turkish Neurosurgery 2002 , Vol 12 , Num 3-4
Emin ÖZYURT, Söhret Ali OĞUZOĞLU, Ahmet Hilmi KAYA, Taner TANRIVERDİ, Tibet KAÇİRA
University of Istanbul, Cerrahpasa Medical Faculty, Department of Neurosurgery, Istanbul Objective: Langerhans' cell histiocytosis is a disease that can involve many organs or remain localized to one organ. The hypothalamus is the most common site of solitary involvement of the central nervous system, and other locations have only been reported rarely. This report describes an unusual case of solitary Langerhans' cell histiocytosis of the occipital lobe, and discusses the clinical findings, radiological features, and treatments for this condition.

Methods: A 4-year-old girl presented with epilepsy of unknown origin. Electroencephalography and diagnostic imaging identified a lesion in her left occipital lobe. The patient was surgically treated with transoccipital lesionectomy and posterior mesial temporal resection.

Results: The histopathological diagnosis was lymphoplasmacytic infiltration of the leptomeninges and the underlying brain. Postoperatively, the patient had transient hemiparesia for 3 weeks, but recovered well otherwise. At 10 months post-surgery, there was no clinical or radiological evidence of recurrence. No adjuvant therapy was needed.

Conclusion: The small number of similar cases in the literature provide little information on which to base decisions about adjuvant therapy after surgical excision. Our patient's outcome, and the results in most cases with long follow-up indicate that total excision of the lesion is satisfactory and sufficient treatment. Keywords : Central nervous system, Langerhans' cell histiocytosis, solitary lesion

Corresponding author : Emin Özyurt, ahmethilmikaya@yahoo.com