Turkish Neurosurgery 2023 , Vol 33 , Num 6
Effect of Pathogenesis-Based Individualized Thrombectomy on Treatment Result and Prognosis of Acute Intracranial Large-Artery Occlusion Patients
Yong-Chang LIU1,Ming-Ming ZHENG1,Yan LI1,Song-Wang XIE1,Qing-Ran LIU1,Jun-Yong WANG1
1Cangzhou Central Hospital, Department of Neurovascular Intervention, Cangzhou City 061000, Hebei Province, China DOI : 10.5137/1019-5149.JTN.37008-21.2 AIM: To explore the effect of pathogenesis-based individualised thrombectomy on the clinical results and prognoses of acute intracranial large-artery occlusion.

MATERIAL and METHODS: A total of 151 patients were included in this prospective study and divided into the control group (stent thrombectomy, 53 cases), a direct aspiration first pass technique (ADAPT) group (52 cases) and the stent group (stent thrombectomy or a combination of stent thrombectomy and ADAPT, 46 cases) based on whether stent or ADAPT was used. We compared and analysed the patients? general information, the National Institutes of Health Stroke Scale (NHISS) score at admission, the time between the end of arteriography and revascularisation, the number of thrombectomies, the modified Rankin scale (mRS) score at three months and complications in the three groups.

RESULTS: Compared with the control group, the time between the end of arteriography and revascularisation in the ADAPT group was significantly reduced (p<0.05), and the patency rate after one thrombectomy significantly increased (p<0.05). The positive prognosis rate was significantly increased in the stent and ADAPT groups compared with the control group (p<0.05).

CONCLUSION: The application of the ADAPT technique in patients with embolism-induced cerebral infarction can reduce the time of revascularisation. The use of stents in patients with atherosclerosis-induced cerebral infarction can increase the patency rate after one thrombectomy. Keywords : Arterial Occlusive Diseases, Pathogenesis, Thrombectomy, Stent

Corresponding author : Yong-Chang LIU, liuyc2021cn@163.com