Turkish Neurosurgery 1993 , Vol 3 , Num 3
Kaya KILIÇ1, Alain CZORNY2, Behiç TÜMER1, Mahir TEVRÜZ1
1Haydarpaşa Numune Hospital Department of Neurosurgery, İstanbul Türkiye
2Service de Neurochirurgie CHU e Besancon - France
The authors study the effectiveness and complications of intraventricular morhphine therapy in the treatment of preterminal cancer pain and compare it with other central and systematic administarions of morphine.

In this series of 35 patients, intraventricular morphine therapy was used when complications of peridural morphine therapy develop or when high dose morphine application by the systematic method had no effect. The quality of analgesia was assessed as "perfect” in 82 % of the cases. The average hospitalizaion period was 2 days. All other systematic sedatives, analgesics and antidepressants were stopped and the initial dose of 0,1 mg/day of morphine never subsequently exceeded 0,2-5 mg/day. Keywords : Intraventricular morphine, Pain, Cancer

Corresponding author : Kaya Kılıç