Turkish Neurosurgery 2012 , Vol 22 , Num 5
Endoscopic Transphenoidal Approach for Fibrous Dysplasia of Clivus, Tuberculum Sellae and Sphenoid Sinus; Report of Three Cases
Ihsan ANIK, Kenan KOC, Burak CABUK, Savas CEYLAN
Kocaeli University, Faculty of Medicine, Pituitary Research Centre and Department of Neurosurgery, Kocaeli, Turkey DOI : 10.5137/1019-5149.JTN.4060-10.0 AIM: Fibrous dysplasia is a benign disease in which medullary bone is replaced by fibro-osseous tissue, and causes distortion and overgrowth of the involved bone and represents about 3% of all bone tumors. There is variability in the manifestation of Fibrous Dysplasia lesions with imaging techniques due to their proportional variations of fibrous to osseous tissue. Radiological differential diagnoses include meningioma, chordoma on MRI and Paget disease on CT imagings.

MATERIAL and METHODS: We report three cases of monostotic fibrous dysplasia, affecting clivus, tuberculum sellae, and sphenoid sinus through the pterygopalatine fossa. We performed pure endoscopic transphenoidal approach for those three cases with the guide of neuronavigation. Extended approach was used via binostril for fibrous dysplasia of clivus and Tuberculum sellae.

RESULTS: Radiologic report revealed chordoma and meningioma for the two cases and fibrous dysplasia for the last case. Total resection of tuberculum sellae, subtotal resection of clivus and partial resection of sphenoid sinus lesions were performed. Pathology diagnosis were fibrous dysplasia in all three patients.

CONCLUSION: Histopathological sampling provided by surgical approach should be obtained to establish the final diagnosis. Endoscopic approaches are convenient for skull base lesions even for biopsy or curative resections providing panoramic view and avoid brain retraction. Keywords : Clivus, Endoscopic transphenoidal approach, Fibrous dysplasia, Tuberculum sellae

Corresponding author : Ihsan Anık, drianik@yahoo.com