Aim:Ischemic stroke remains one of the leading causes of death and disability worldwide and ca-rotid stenosis is the leading etiology of ischemic strokes of non-cardiac origin. The chronic inflammatory process and pro-inflammatory state in carotid stenosis seem to be the most im-portant underlying factor in carotid occlusion. In addition to medical therapy and carotid ar-tery stunting (CAS) in the treatment of carotid stenosis, carotid endarterectomy (CEA) is the main surgical treatment of carotid stenosis and its prognosis is the main subject of our study.Material and Methods:As a retrospective single center study, we measured the systemic immune inflammation index (SII) and other systemic inflammatory parameters to estimate the mortality and morbidity of patients undergoing CEA. These parameters include inflammatory markers which are included in routince preoperative haematologic tests like CBC. Results:After the analysis of the collected datas from 72 patients, the results showed that inflammato-ry indices were significantly different in patients with different clinical coruse.Conclusion:Inflammatory parameters calculated from routine preoperative hematologic parameters proved to be important predictive parameters that can be used in mortality/morbidity estimation of patients scheduled for CEA.