Turkish Neurosurgery
2010 , Vol 20 , Num 2
Fractionated Gamma Knife Radiosurgery for Optic Nerve Tumors: A Technical Report
1,2,3,5,6,7,8Gazi University, Faculty of Medicine, Neurosurgery Department, Ankara, Turkey4Gazi University, Faculty of Medicine, Radiation Oncology Department, Ankara, Turkey DOI : 10.5137/1019-5149.JTN.1681-09.3 AIM: The main purpose of this report is to demonstrate the effects of fractionated radiosurgery regimens in the management of optic gliomas
MATERIALS and METHODS: Two patients suffering from progressive loss of vision due to optic nerve gliomas were treated with Gamma Knife radiosurgery in three fractions within three consecutive days instead of a single dose regimen. Patients were followed for 42 and 39 months respectively.
RESULTS: The treatment modality was well tolerated by the patients with radiological and neurological tumor control after 42 and 39 months of follow up. There were no additional complications.
CONCLUSION: Fractionated regimens of Gamma Knife surgery offer a very good alternative for lesions such as optic glioma and optic nevre sheath meningioma.
Keywords : Fractionation, Gamma knife radiosurgery, Linear quadratic model, Optic nerve tumors, Stereotactic techniques