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¹Department of Neurosurgery, School of Medicine, University of Dokuz Eylül, Izmir, Turkey A case with giant cavernous hemangioma in the cavernous sinus is reported. The patient had a 5-month history of headache and visual symptoms. Computerized tomography (CT) and magnetic resonance imaging (MRI) studies demonstrated a lesion of the cavernous sinus in the left middle fossa. Only a biopsy of the cavernous malformation of cavernous sinus was performed during the first surgery because of uncontrollable haemorrhage during surgery. After the operation, radiation therapy was performed. Five years later, the lesion was totally removed because of its gradual enlargement. The second surgery was uncomplicated except for partial third nerve palsy. Ten years after the operation, the patient was in good health and there was no recurrence of the cavernous angioma. Keywords : Cavernous malformation, Cavernous sinus, Magnetic resonance imaging, Radiation therapy, Surgery