Turkish Neurosurgery
2008 , Vol 18 , Num 2
Macrocephaly and Bitemporal Arachnoid Cysts not Associated with Glutaric Aciduria Type I in a Child
1,5Mustafa Kemal University, Tayfur Ata Sökmen Medical School, Department of Neurosurgery, Hatay/Turkey2Mustafa Kemal University, Tayfur Ata Sökmen Medical School, Department of Neurology, Hatay/Turkey
3Mustafa Kemal University, Tayfur Ata Sökmen Medical School, Department of Pediatrics, Hatay/Turkey
4Mustafa Kemal University, Tayfur Ata Sökmen Medical School, Department of Pediatric Surgery, Hatay/Turkey A 45-month-old child who had bitemporal arachnoid cysts and macrocephaly unrelated to glutaric aciduria type 1 (GA 1) was reported. The patient was admitted to the emergency unit after head trauma at 11 months of age. CT and MRI showed bitemporal arachnoid cysts (BACs). Acylcarnitine profile was normal in serum using tandem mass spectrometry. Urine and blood screening tests were within normal range for metabolic disorders. There were no unusual organic acids in urine and blood samples. No additional clinical findings of metabolic disorders such as GA 1 developed during follow-up. The majority of children affected with GA 1 have macrocephaly and BACs on CT or MRI. These signs should alert neurosurgeons to the possibility of GA 1. Neurosurgeons evaluating patients with head trauma or suspected non-accidental head injury should include GA 1 in the differential diagnosis of BACs associated with macrocephaly, and an evaluation should be performed. Keywords : Arachnoid cyst, Bitemporal arachnoid cysts, GA 1, Glutaric aciduria type 1, Head trauma, Macrocephaly, Metabolic disorder