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¹Baskent University Medical Facu1ty, Department of Neurosurgery, Ankara, Turkey
²New York University Medical Facu1ty, Department of Radiology , New York, USA
³University of Virginia Medical Facu1ty, Department of Anesthesiology, Charlottesville, USA Lysophosphatidic acid is the simplest phospholipid known. It is produced by platelets, endothelial cells, leukocytes, some cancer cells, astrocytes, and injured fibroblasts. Lysophosphatidic acid is thought to play a role in platelet aggregation and fibrosis. Since in radiation injury, platelet aggregation on endothelial cell surfaces and fibrin formation are the main events, lysophosphatidic acid might play a major role in radiation injury. Keywords : Lysophosphatidic acid, phospholipids, radiation