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Gülhane Military Medical SchooL,Department of Neurosurgery, Ankara, Turkey The result of surgical therapy of sellar region neoplasms in 107 patients treated between 1986-1995 is reviewed. In this series there were 89 pituitary adenomas, 8 meningiomas, 9 craniopharyngiomas, and one mucocele. Transcranial, transphenoidal, and combined transcranial-transsphenoidal approaches were used for surgical therapy. Three patients died postoperatively. Ten patients had complications related to surgery; CSF leak in three patients, diabetes insipidus in four, meningitis in two, and abscess in one. Radiation therapy was administered to four patients postoperatively. Keywords : Craniopharyngioma, meningioma, pituitary adenoma, sellar region