Turkish Neurosurgery 2024 , Vol 34 , Num 6
Efficacy and Safety Assessment of LVIS Jr Device in Treating Wide-Neck Aneurysms: A Comprehensive Systematic Review and Single-Arm Meta-Analysis
Marcelo Porto SOUSA1,Guilherme Nunes MARQUES1,Livia Viviani de ABREU1,Filipi Fim ANDREÃO1,Leonardo de Barros OLIVEIRA2,Gabriel VERLY1,Sávio BATISTA1,Guilherme Melo SILVA1,Raphael Muszkat BESBORODCO3,Raphael BERTANI4
1Federal University of Rio de Janeiro, Faculty of Medicine, Rio de Janeiro - Rio de Janeiro, Brazil
2State University of Ponta Grossa, Faculty of Medicine, Ponta Grossa - Paraná, Brazil
3Rusk Rehabilitation, NYU Langone Health, New York - New York, United States
4University of São Paulo, Department of Neurosurgery, São Paulo - São Paulo, Brazil
DOI : 10.5137/1019-5149.JTN.46167-23.2 AIM: To evaluate the usage and the effectiveness of LVIS Jr device technology in managing wide-neck intracranial aneurysms.

MATERIAL and METHODS: PubMed, Embase, and Web of Science databases, comprising studies with outcomes related to LVIS Jr use in wide-neck intracranial aneurysms were searched systematically. Data was extracted from the selected articles and subjected to statistical analysis.

RESULTS: Among 886 initially identified articles, 20 studies met our inclusion criteria, comprising a total of 557 patients. Our analysis revealed a 96% final occlusion rate under common effects and 93% under random effects, with substantial heterogeneity (I² = 69%). Good clinical outcomes were observed in 99% of cases with low heterogeneity (I² = 27%). Mortality rates were extremely low, with only one reported death out of 499 patients across 18 studies, resulting in a 0% mortality rate for common and random effects and no heterogeneity (I² = 0). Complications occurred in 44 of 482 patients, yielding a 6% rate in the common effect model and 6% in the random effects model, with nonsignificant heterogeneity (I² = 25%).

CONCLUSION: LVIS Jr observed a favorable rate of final occlusion and good clinical outcomes, and the low mortality and complication rates highlight its safety in the treatment of wide-neck aneurysms. Keywords : Wide-neck, Aneurysm, Stent, LVIS Jr

Corresponding author : Marcelo Porto SOUSA, mportosousa@gmail.com