Issue release date: 13.09.2024
2Ankara University, School of Medicine, Department of Biostatistics Ankara, Türkiye
3Pamukkale University, School of Medicine, Department of Radiology, Denizli, Türkiye
4Odak Hospital, Department of Neurosurgery, Denizli, Türkiye DOI : 10.5137/1019-5149.JTN.44895-23.2 AIM: To compare T1-weighted contrast-enhanced (T1+C) with fast imaging employing steady-state acquisition (FIESTA) magnetic resonance imaging (MRI) sequences to protect healthy brain tissue during meningioma treatment with Gamma-Knife radiosurgery (GKRS).
MATERIAL and METHODS: After reviewing the data of 54 patients with solitary meningioma who underwent GKRS between January 2020 and June 2022, demographic characteristics were noted, tumor volumes on T1+C and FIESTA MRI sequences were measured, and sequences were compared. The patients were then divided into two groups according to the presence of invasion to intracranial venous sinuses (groups 1 and 2, respectively). SPSS 11.5 software was used for data analysis, with the level of significance set at 0.05.
RESULTS: While no significant age and tumor size differences were observed between groups 1 and 2, sinus invasion was significantly higher among males. Tumor volumes measured in both groups were significantly smaller on FIESTA sequences than on T1+C sequences.
CONCLUSION: The T1+C sequence has been the primary imaging method because of meningiomas? high contrast enhancement feature. However, the T1+C sequence during GKRS planning is an effective imaging method in treating meningiomas; FIESTA sequences can more precisely delineate the tumor border. In this study, we consider that using the FIESTA/CISS sequence MRI for planning meningioma therapy with Gamma-Knife can reduce target volume and prevent irradiation of healthy brain tissue.
Keywords : FIESTA/CISS, Meningioma, Gamma-Knife radiosurgery, Magnetic resonance imaging, Image-guided neurosurgery, Radiosurgery, MRI sequences