MATERIAL and METHODS: According to the PRISMA guidelines, we searched the literature on sellar floor reconstruction in endoscopic sellar surgery. Fixed- or random-effects meta-analysis was used to pool the rate of return to postoperative cerebrospinal fluid (poCSF) leakage, repair operations, postoperative hospitalization, complete resection, infection, lumbar drainage (LD), and operative duration.

RESULTS: A total of six studies involving 723 participants were included in the current meta-analysis. The pooled results demonstrated that patients in the dural suturing group had a lower incidence of poCSF leakage [odds ratio (OR), 0.18; 95% confidence interval (CI), 0.07 ? 0.44; p=0.0002] and repair operation [OR, 0.24; 95% CI, 0.07 ? 0.78; p=0.02], as well as a shorter hospitalization period [standardized mean difference (SMD), -0.45; 95% CI, -0.62 ? -0.28; p<0.00001]. There was no significant difference between the two groups in terms of the complete resection [OR, 1.06; 95% CI, 0.62 ? 1.80; p=0.84], postoperative infection [OR, 0.49; 95% CI, 0.21 ? 1.15; p=0.10] and lumbar drainage (LD) [OR, 0.28; 95% CI, 0.06 ? 1.23; p=0.09]. Additionally, the dural suturing group may require a longer operative duration [SMD, 0.29; 95% CI, 0.02 ? 0.56; p=0.03].

CONCLUSION: The results suggest that dural suturing can be advantageous in reducing postoperative complications and shortening postoperative hospitalization following neuroendoscopic surgery in the sellar region without increasing the risk of infection. Keywords : Neuroendoscope, Sellar base repair, Cerebrospinal fluid leak, Dural suture, Meta-analysis