Issue release date: 12.11.2024
2Baskent University Faculty of Medicine, Department of Radiology, Ankara, Turkey
3The Digital Transformation Office of The Presidency of The Republic of Turkey, The Artificial Intelligence and Big Data Unit, Ankara, Turkey
4Gazi University Faculty of Medicine, Department of Neurosurgery, Division of Pediatric Neurosurgery, Ankara, Turkey
5Gazi University Faculty of Medicine, Department of Neurosurgery, Ankara, Turkey DOI : 10.5137/1019-5149.JTN.29217-20.2 AIM: To describe a deep convolutional generative adversarial networks (DCGAN) model which learns normal brain MRI from normal subjects than finds distortions such as a glioma from a test subject while performing a segmentation at the same time.
MATERIAL and METHODS: MRIs of 300 healthy subjects were employed as training set. Additionally, test data were consisting anonymized T2-weigted MRIs of 27 healthy subjects and 27 HGG patients. Consecutive axial T2-weigted MRI slices of every subject were extracted and resized to 364x448 pixel resolution. The generative model produced random normal synthetic images and used these images for calculating residual loss to measure visual similarity between input MRIs and generated MRIs.
RESULTS: The model correctly detected anomalies on 24 of 27 HGG patients? MRIs and marked them as abnormal. Besides, 25 of 27 healthy subjects? MRIs in the test dataset detected correctly as healthy MRI. The accuracy, precision, recall, and AUC were 0.907, 0.892, 0.923, and 0.907, respectively.
CONCLUSION: Our proposed model demonstrates acceptable results can be achieved only by training with normal subject MRIs via using DCGAN model. This model is unique because it learns only from normal MRIs and it is able to find any abnormality which is different than the normal pattern.
Keywords : Artificial intelligence, Deep learning, Glioma, Machine learning, Segmentation