Turkish Neurosurgery
1993 , Vol 3 , Num 3
OCCIPITO-CERVICAL EXTRACRANIAL SCHWANNOMA TRANSFORMING INTO A MALIGNANT PERIPHERAL NERVE SHEATH TUMOUR (MPNST)
1University of Istanbul Istanbul School of Medicine, Department of Neurosurgery,2Dokuz Eylül University, School of Medicine, Department of Neurosurgery, İzmir
3Dokuz Eylül University, School of Medicine, Department of Pathology, İzmir Benign solitary schwannomas arise often from cranial nerves, but they may be located at any part of the body, especially in the face and neck region. A 17-year old woman was accepted in our clinic for an extracranially growing tumour at the occipito-cervical region. She had been operated twice in another hospital for this tumour before she was admitted to our clinic. The patient was reevaluated and the tumour was extirpated. The histopathologic examination was confirmed the previous diagnosis of shwannoma. But ten months later the patient was reoperated for a growing tumoral mass at the same place. After radical resection pathologic examination revealed malignant transformation from schawannoma to neurogenic sarcoma. Then the radiotherapy was planned, so 3500 rad was applied and the patient was seen 5 years later.
In schwannoma. malignant transformation and role of radiotherapy combined with radical resection on its treatement were discussed.
Keywords : Benign sehwannoma, malignant periperal nerve sheath tumour, peripheral nerve tumours