Issue release date: 12.11.2024

 
Turkish Neurosurgery 2018 , Vol 28 , Num 2
Learning Curve in Anatomo-Electrophysiological Correlations in Subthalamic Nucleus Stimulation
Dušan HRABOVSKY1,Marek BALAZ2,Martina BOCKOVA3,Věra FEITOVA4,Zdeněk NOVAK1,Jan CHRASTINA1
1Masaryk University, Medical Faculty, St. Anne?s Hospital, Department of Neurosurgery, Brno, Czech Republic
2Masaryk University, Medical Faculty, St. Anne?s Hospital, First Department of Neurology, Brno, Czech Republic
3Masaryk University, Central European Institute of Technology, Brno, Czech Republic
4Masaryk University, Medical Faculty, St. Anne?s Hospital, Department of Imaging Techniques, Brno, Czech Republic DOI : 10.5137/1019-5149.JTN.19450-16.0 AIM: Advances in neuroradiological planning techniques in deep brain stimulation have put the need for intraoperative electrophysiological monitoring into doubt. Moreover intraoperative monitoring prolongs surgical time and there is potential association between the use of microelectrodes and increased incidence of hemorrhagic complications. The aim of this study was to analyze the correlation between the anatomically planned trajectory and the final subthalamic electrode placement after electrophysiological monitoring in patients with Parkinson"s disease and its change with the increasing experience of the surgical team.

MATERIAL and METHODS: The trajectories of right (first implanted) and left electrodes were compared in the first 50 patients operated on (Group 1) and the next 50 patients (Group 2).

RESULTS: In Group 1, 52% of central trajectories were on the right and 38% on the left; in Group 2, the percentage of central trajectories was 76% on the right and 78% on the left; the difference was statistically significant (p=0.021 and 0.001). The difference in the percentage of posterior trajectories reflecting brain shift between the right and left sides was statistically insignificant in Groups 1 (26% and 28%, p=0.999) and 2 (18% and 12%, p=0.549). The percentage of bilateral central electrodes was 14% and 62% in Groups 1 and 2, respectively.

CONCLUSION: The correlation between anatomically planned trajectory and final electrode placement markedly improves with the number of patients. However the significant percentage of patients with final electrode trajectory differing from anatomically planned target supports the use of intraoperative monitoring. Keywords : Deep brain stimulation, Parkinson"s disease, Subthalamic nucleus, Frame-based stereotaxy, Intraoperative monitoring

Corresponding author : Jan CHRASTINA, jan.chrastina@fnusa.cz