Issue release date: 12.11.2024

 
Turkish Neurosurgery 2013 , Vol 23 , Num 5
Does Probe's Eye Subthalamic Nucleus Length on T2W MRI Correspond with Microelectrode Recording in Patients with Deep Brain Stimulation for Advanced Parkinson's Disease?
Ersoy KOCABICAK1, Dursun AYGUN2, Ilkay OZAYDIN3, Ali JAHANSHAHI4, Sonny K. H TAN5, Musa ONAR2, Omer BOKE6, Murat KURT7, Hatice GUZ6, Murat TERZI2, Onur ALPTEKIN8, Yasin TEMEL9
1Ondokuz Mayis University, Faculty of Medicine, Department of Neurosurgery, Samsun, Turkey
2Ondokuz Mayis University, Faculty of Medicine, Department of Neurology, Samsun, Turkey
3Ondokuz Mayis University, Faculty of Medicine, Department of Radiology, Samsun, Turkey
4Maastricht University, Faculty of Medicine, Department of Neuroscience, Maastricht, Netherlands
5Aachen University, Faculty of Medicine, Department of Neurosurgery, Aachen, Germany
6Ondokuz Mayis University, Faculty of Medicine, Department of Psychiatry, Samsun, Turkey
7Ondokuz Mayis University, Faculty of Medicine, Department of Psychology, Samsun, Turkey
8Medtronic Inc., Neuromodulation, Istanbul, Turkey
9Maastricht University, Faculty of Medicine, Department of Neurosurgery, Maastricht, Netherlands DOI : 10.5137/1019-5149.JTN.8328-13.0 AIM: Subthalamic nucleus (STN) deep brain stimulation (DBS) has become a well-accepted treatment for patients with advanced Parkinson’s disease (PD). During surgical planning for DBS, the length of the STN is taken into account and verified during microelectrode recording (MER) intraoperatively. Here, we addressed the question to which extent the length of the STN measured with the T2 weighted MRI in the probe’s eye view corresponded with the intraoperatively determined length of the STN with MER.

MATERIAL and METHODS: We included 10 consecutive Parkinson’s disease patients who underwent STN DBS surgery. The length of the STN in the probe’s eye view mode was calculated along the trajectory of the central MER electrode crossing the STN.

RESULTS: Our analysis showed no statistical difference between the length of the STN measured with the T2 weighted probe’s eye view mode and the MER (right STN length 5.8 ± 0.9 mm MRI vs. 6.3 ± 0.5 mm MER, p>0.05; left STN length 5.6 ± 0.4 mm MRI vs 5.8 ± 1 mm MER, p>0.05).

CONCLUSION: This means that the entry and the exit of the STN can be adequately estimated using the probe’s eye view preoperatively. Keywords : Parkinson’s disease, Subthalamic nucleus, Microelectrode recording, Magnetic resonance imaging, Deep brain stimulation

Corresponding author : Ersoy Kocabıcak, ersoykocabicak@gmail.com