Issue release date: 12.11.2024
2Firat University Hospital, Department of Neurosurgery, Elazig, Turkey
3Firat University Hospital, Department of Radiology, Elazig, Turkey
4Firat University Hospital, Department of Biochemistry, Elazig, Turkey DOI : 10.5137/1019-5149.JTN.6982-12.1 AIM: To evaluate the correlation between the dimensions of ischemic and hemorrhagic lesions detected by diffusion MRI and the changes in lesion dimensions with serum NT-proBNP levels in mild and moderate head trauma.
MATERIAL and METHODS: 30 patients were assessed in our study. A control group of 10 individuals with no trauma history was formed in order to establish normal serum NT-proBNP values. Patients underwent brain diffusion MRI 24 and 48 hours following admittance. Their plasma NT-proBNP levels were checked at the same stages.
RESULTS: The correlation between the values of 24th and 48th hour Intra-axial hemorrhage (IAHEM) and Intra-axial ischemia (IAISC) and the values of 24th and 48th hour NT-proBNP was established as statistically significant.
CONCLUSION: It was observed that the serum NT-proBNP values could be higher in patients with wide intra-axial lesion following head trauma than patients with smaller intra-axial lesions. In addition, the fact that it has been established that the serum NT-proBNP values of patients with increasing cerebral parenchymal lesion dimensions on the advancing hours after the trauma increase suggests that serum NTproBNP values may be significant in the follow-up of the dimensions of cerebral parenchymal damage.
Keywords : Head injuries, NT-proBNP, Diffusion MRI, Ischemia, Hemorrhage