Turkish Neurosurgery 2010 , Vol 20 , Num 2
Fractionated Gamma Knife Radiosurgery for Optic Nerve Tumors: A Technical Report
Gokhan KURT1, Mehmet TONGE2, Alp Ozgun BÍRCEK3, Eray KARAHACIOGLU4, Ozgur GUREL5, Kemali BAYKANER6, Necdet CEVIKER7, Ůukru AYKOL8
1,2,3,5,6,7,8Gazi University, Faculty of Medicine, Neurosurgery Department, Ankara, Turkey
4Gazi University, Faculty of Medicine, Radiation Oncology Department, Ankara, Turkey
DOI : 10.5137/1019-5149.JTN.1681-09.3 AIM: The main purpose of this report is to demonstrate the effects of fractionated radiosurgery regimens in the management of optic gliomas

MATERIALS and METHODS: Two patients suffering from progressive loss of vision due to optic nerve gliomas were treated with Gamma Knife radiosurgery in three fractions within three consecutive days instead of a single dose regimen. Patients were followed for 42 and 39 months respectively.

RESULTS: The treatment modality was well tolerated by the patients with radiological and neurological tumor control after 42 and 39 months of follow up. There were no additional complications.

CONCLUSION: Fractionated regimens of Gamma Knife surgery offer a very good alternative for lesions such as optic glioma and optic nevre sheath meningioma. Keywords : Fractionation, Gamma knife radiosurgery, Linear quadratic model, Optic nerve tumors, Stereotactic techniques

Corresponding author : Mehmet Tonge, tonge_m@yahoo.com